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Aviva also rank highly. Methylation of proteins from budding yeasts (resembling Ipl Aurora kinase and ribosomal proteins) and crops (Rubisco subunits) has also been reported 11 , 183 - 185 It is conceivable that many proteins can be modified by lysine methylation, in addition to different varieties of PTMs.
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KMTs catalyze mono-, di-, or tri-methylation by transfering one, two, or three methyl groups, respectively, from S-adenosyl-L-methionine to the ε-amino group of a lysine residue.
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The enzymes concerned in lysine methylation had been first discovered to target histone and thus had been initially named histone methyltransferases and histone demethylases, following the naming mannequin for histone acetyltransferase and histone deacetylase.
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